01
Speed
The time it takes to brew a cup of coffee
Koffee runs more than 100 times faster than current alternatives. It only takes minutes to run a simulation.
Unbinding kinetics in the time it takes to make a cup of coffee
Our ground-breaking solution for unbinding kinetics enables pharma and biotech companies to iterate smarter, save time & money and derisk the drug discovery process
Dive into the details
A new approach to drug discovery
Key insights for better drug discovery
01
Iterate smarter
Simulate unbinding kinetics within minutes. You can get valuable insights at several steps in the drug discovery process.
02
Save time & money
Our solution can complement time consuming and expensive laboratory experiments, supporting faster design cycles and giving you key insights for more compounds.
03
De-risk drug discovery
By gaining insights to a key measure such as unbinding kinetics earlier in the process, we enable you to de-risk drug discovery!
Koffee Highlights
Our revolutionary unbinding kinetics solution comes with several benefits compared to current methods
02
Accuracy
Performance experimentally validated
We have performed thorough benchmarking to demonstrate performance. Comparison to experimental unbinding rates achieved excellent agreement across a range of systems.
03
Applicable across targets & ligands
Wide range of targets and ligands
Koffee performs strongly across different target classes and diverse ligand chemistry. We have benchmarked across popular drug targets including kinases, GPCRs and molecular chaperones.
04
Quantum-ready
Our solution is quantum-ready
Koffee is based on Kvantify’s novel dynamics engine that is intrinsically ready for quantum. Classical methods provide speed; quantum methods will bring accuracy.
What you will get
01
Unbinding rates
Koffee predicts unbinding kinetics rates, a key metric indicating how long a drug interacts with the target
02
Ranking of ligands
Koffee ranks ligands according to their kinetic profile, providing rational insights into which molecules to take forward in the drug discovery process
03
Scalability
Koffee inherently scales: large numbers of calculations can be run simultaneously to provide fast results even early in the drug design process
Get in touch
Our groundbreaking unbinding kinetics solution comes with several benefits compared to current methods
Get in touch
