Koffee offers a fully physics-based approach, delivering clear mechanistic insights for drug discovery. Our algorithm enhances throughput without sacrificing accuracy, and it also supports unbinding kinetics.
Binding affinity & kinetics in the time it takes to make a cup of coffee
Our drug discovery platform, Koffee, enables pharma and biotech companies to improve the quality of the compounds they test in the lab by leveraging our high-speed, accurate, physics-based methods.
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Predict binding affinity and unbinding kinetics with calculations that are orders of magnitudes faster than current methods.
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Ensure reliable results with high accuracy - on par with comparable state-of-the-art methods.
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Gain in-depth, actionable insights through physics-based approaches, enhancing interpretability.
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Deploy molecular design tasks at speed, with iterative design-make-test-analyse cycles designed for automation.
Reinventing Binding Affinity
This latest addition to our platform delivers physics-based binding affinity predictions, that are orders of magnitude faster than current methods with comparable accuracy.
What you will get
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Koffee delivers accurate predictions that scale efficiently, allowing companies to analyze large datasets and make informed decisions.
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Since Koffee is fully physics-based, it provides a clear mechanistic understanding to guide challenging compound design tasks in real time.
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Benchmarked on a diverse set of proteins and ligands, Koffee has proven to be on par with respect to accuracy and in a small fraction of the time compared to state-of-the-art methods.
Dive into the science
Case Study: Tetra Pharm x Kvantify
From thousands of compounds to a handful
in a matter of weeks
We partnered with Tetra Pharm Technologies to accelerate their drug discovery by rapidly screening thousands of ligands and identifying top candidates.
- Reduced Screening Time: Koffee’s kinetics simulations cut screening time from months to weeks
- Cost Efficiency: Reduced reliance on costly lab-based screening methods.
- Data-Driven Insights: Delivered SAR-based insights, refining compound selection.
A new approach to drug discovery
Our kinetics methods, Koffee unbinding kinetics comes with several benefits compared to current methods and is a product of our physics-based approach to drug discovery.
Key insights for better drug discovery
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Simulate binding affinity and unbinding kinetics within minutes. You can get valuable insights at several steps in the drug discovery process.
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Our solution can complement time consuming and expensive laboratory experiments, supporting faster design cycles and giving you key insights for more compounds.
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By gaining insights to a key measure such as binding affinity and unbinding kinetics earlier in the process, we enable you to de-risk drug discovery!
Reach out for an introduction
Our novel physics-based methods comes with several benefits and we are more than happy to schedule an introduction call to elaborate on how we can collaborate.